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Testosterone and Zinc
Stimulation of the Akt pathway is crucial for MPS. The classical activation through the IGF-1 receptor is not the only possible way of activation. Akt pathway can be also stimulated through the beta-2 adrenergic receptor. Testosterone is androgen with well-known anabolic effect. A big market is created around supplements which are supposed to increase testosterone levels. However, in a study published in Frontiers of Physiology, testosterone levels of 49 resistance-trained men were assessed before and after 12 weeks of resistance training and the effectiveness of stimulating testosterone was questioned.
After the 12-week exercise program, men were divided into responder and non-responder groups according to the cross-section area of muscle fibres in their thighs. Also, their hormone levels were measured before and after the 12-week program. There was no significant difference in testosterone levels between non-responders and responders. No difference was found in other tested hormones (IGF-1, dehydroepiandrosterone, growth hormone, luteinizing hormone). All of these hormones are proposed to be anabolic, therefore these results are surprising.
The difference between responders and non-responders was found in the content of adrenergic receptors that testosterone binds to. These results suggest that the levels of circulating testosterone are not reflected in gained muscle mass. Rather, it is important how sensitive your body is to testosterone.
Indeed, it can be objected that injections of testosterone stimulate muscle growth, but this is likely because injections spike testosterone levels dramatically (sometimes by 600%) above the physiological range. In this range, testosterone can have drastic adverse effects like infertility, aggressive behaviour, high blood pressure and others. Testosterone injections can also become addictive.
According to this research spiking your testosterone levels naturally also won’t have much effect as the body’s response to physiological levels of insulin is dependent on the content of your adrenergic receptors that testosterone binds to.
Fortunately, it is possible to manipulate the functional properties of beta-2 adrenergic receptors. Zinc was shown both in human and animals to increase the affinity of receptor to its agonists. In other words, zinc makes our receptors more sensitive to testosterone and its anabolic effect. Old studies assessing zinc deficiency support the notion that zinc is an important factor in MPS.
References
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189473/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189473/
http://molpharm.aspetjournals.org/content/61/1/65.long
https://eje.bioscientifica.com/view/journals/eje/119/2/acta_119_2_003.xml
https://pubmed.ncbi.nlm.nih.gov/2432920/
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Losing weight can be a daunting task that many of us will try to accomplish at some point in our lives. However, when it comes to weight loss products and supplements flooding the market, it can be difficult to weed out the ones that actually work. One of the recent trends in the weight loss industry is weight loss gummies. Do weight loss gummies work, or are they just another fad?
Exploring the Effectiveness of Weight Loss Gummies
Weight loss gummies are a type of weight loss supplement that promises to help users to lose weight by reducing appetite, increasing metabolism, and promoting fat burning. Generally, such gummies are made from a mixture of green tea extract, caffeine and garcinia cambogia, all the ingredients that may help to reduce weight.
Besides the obvious benefit of having to take fewer supplements to see results, one major advantage of weight loss gummies could be that they are easy to take with you wherever you go. Pre-portioned and in various delicious flavours, weight loss gummies can be a fun way of incorporating supplements into your day compared with pills or powders. And because they are so tasty, weight loss gummies can make it easier to stick to a weight loss plan compared with other supplements.
But weight loss gummies deserve wariness and scepticism. Research shows that some weight loss gummy ingredients have been linked to weight loss, while others remain controversial in the minds of health experts. Review the ingredients and do extensive research into the products you are considering to see what health experts have to say. For extremely valuable suggestions about implementing a healthy and permanent weight loss plan, speak to your healthcare team.
Understanding the Potential Risks of Weight Loss Gummies
As with other weight loss supplements, weight loss gummies can produce side effects and have associated risks. Given the higher fibre content of many weight loss gummies, dietary supplementation with these products may cause some people to experience bloating, gas and diarrhoea. Depending on the gummies’ ingredients, such as caffeine, an unusually high number of these products may induce jittery sensations, sleeplessness and elevated heart rates in some women and men.
Another concern regarding weight loss gummies is overconsumption. Because they are usually marketed as a ‘tasty treat’ and weight loss ‘supplement’, it can be easy to eat more than the recommended dose in an effort to ‘speed up’ the results. To add to this, overconsumption of weight loss gummies can result in adverse effects, and it doesn’t necessarily lead to more of a fasting response, nor does it replicate fasting.
Conclusion
In summary, the exact effectiveness of weight loss gummies is still controversial to the scientific community. Although there are cases where these gummies can lead to weight loss, they should still be approached by exercising caution and additionally, not solely relying on them as a source of means to lose weight. Weight loss products, in general, should be used in combination with a healthy diet, physical activity and not replacing necessary meals that the body requires. Always consult with a medical professional before starting a new supplement regimen.
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Shark Tank is a popular television show where entrepreneurs pitch their business ideas to a panel of investors known as the “sharks.” One common theme that has emerged from the show is the importance of maintaining a healthy lifestyle, including managing one’s weight. In this article, we will explore some insights from Shark Tank episodes on how to lose weight effectively.
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One of the key takeaways from watching Shark Tank is the importance of setting achievable weight loss goals. Many entrepreneurs on the show have shared their struggles with weight management and how it has impacted their overall well-being. By setting realistic goals and creating a plan to achieve them, individuals can make meaningful progress towards a healthier lifestyle.
Another important lesson from Shark Tank is the value of accountability and support in weight loss efforts. The sharks often emphasize the importance of having a strong support system in place, whether it be friends, family, or a professional coach. By surrounding oneself with people who encourage and motivate them, individuals are more likely to stay on track with their weight loss goals.
Additionally, Shark Tank has highlighted the benefits of incorporating regular exercise into one’s routine as a key component of weight loss. Whether it’s through an innovative fitness product or a unique workout regimen, the show has showcased various ways in which physical activity can help individuals achieve their desired weight loss results.
Success Stories from the Show
Several entrepreneurs who have appeared on Shark Tank have shared their weight loss success stories and the strategies they used to achieve their goals. For example, one contestant developed a meal delivery service that focused on providing nutritious and portion-controlled meals to help customers lose weight effectively. By following a structured meal plan and incorporating regular exercise, many customers saw significant results in their weight loss journey.
Another success story from Shark Tank involves a fitness app that provides personalized workout plans and nutrition guidance to help users reach their weight loss goals. By utilizing technology to track progress and stay motivated, individuals were able to stay accountable and make sustainable lifestyle changes that led to long-term weight loss success.
Furthermore, some entrepreneurs on Shark Tank have created innovative weight loss products such as smart scales, meal prep containers, and fitness gadgets that have helped individuals stay on track with their health and wellness goals. By leveraging these tools and resources, many people have been able to overcome obstacles and make positive changes towards a healthier lifestyle.
Expert Advice on Weight Loss
Aside from the stories shared on Shark Tank, the show often features guest experts who provide valuable insights and advice on weight loss and healthy living. These experts, which may include nutritionists, personal trainers, and medical professionals, offer practical tips and strategies for achieving and maintaining a healthy weight.
Some common advice from these experts includes focusing on whole, nutrient-dense foods, staying hydrated, getting an adequate amount of sleep, and managing stress levels to support weight loss efforts. By making small, sustainable changes to their daily habits, individuals can improve their overall health and well-being while working towards their weight loss goals.
In conclusion, Shark Tank offers valuable insights and inspiration for individuals looking to lose weight and improve their overall health. By learning from the experiences of entrepreneurs who have successfully navigated their own weight loss journeys, viewers can gain valuable knowledge and motivation to make positive changes in their own lives. Whether it’s through setting realistic goals, seeking accountability and support, incorporating regular exercise, or leveraging innovative products and services, there are many strategies available to help individuals achieve their weight loss goals and lead a healthier, happier life.
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Luxe ACV Keto Gummies are specially formulated to provide all the benefits of apple cider vinegar (ACV) in a convenient and delicious gummy form. ACV has been touted for its numerous health benefits, including supporting weight loss, improving digestion, and boosting immunity. With Luxe ACV Keto Gummies, you can enjoy all these benefits and more without having to deal with the strong taste of liquid ACV.
These gummies also contain exogenous ketones, which can help your body enter ketosis faster and more efficiently. Ketosis is a metabolic state where your body burns fat for energy instead of carbs, making it easier to lose weight and maintain a healthy lifestyle. By incorporating Luxe ACV Keto Gummies into your daily routine, you can support your body’s natural fat-burning processes and reach your weight loss goals more effectively.
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I have narrowed down my top 3 to: Green Tea or more specifically its most active ingredient EGCG , Branched Chain Amino Acids perhaps most predominately Leucine, and Medium chain triglycerides namely the 8-carbon saturated fatty acid called Caprylic Acid.
Let me explain why!
Green Tea
I definitely wouldn't say that green tea is the most popular synergistic supplement with a ketogenic diet, but it is highly effective in its ability to reduce the tendency to absorb fat and increase the ability to burn fat. It comes down to the potent fat oxidation that green tea promotes from it being a rich source of polyphenol catechins. In particular EGCG or epigallocatechin gallate is the most active of the catechins in green tea and is primarily responsible for the antioxidant, anti inflammatory, and metabolic effects. To break this down even further the boost in fat metabolism comes from EGCG's direct effect on proteins and phospholipids in the plasma membrane that up regulate mitochondrial function, which we know is the energy factory for all cells in our body, therefore increasing the rate at which fatty acids are metabolized. Or in other words increasing our use of fat to produce energy. In a ketogenic diet where we are primarily depending on fat metabolism for energy, we can see how this boost in fat oxidation can provide improvements in ketone production and can promote further weight loss in the form of body fat or adipose tissue. In addition the naturally occurring caffeine in green tea works synergistically to boost metabolism.
BCAA
The branched chain amino acids consist of three essential amino acids, meaning they must be consumed and can not be manufactured inside the body, these 3 are: leucine, isoleucine, and valine. We know that in metabolism fueled by glucose protein and amino acid breakdown is inevitable which is what prompts athletes trying to build lean muscle mass to supplement BCAAs. While the ketogenic metabolism has been proven to spare these BCAAs, they also play larger rolls, making their heightened levels even more valuable. As discussed in the "ketogenic effects of muscle building" video, Leucine is able to take on the role of insulin, that is suppressed in a ketogenic diet, and effectively promote muscle protein synthesis. On a smaller cellular level these BCAAs are able to replenish the intermediates for cellular energy cycles, which is a huge benefit in a ketogenic diet were glycolysis is lowered and cellular pyruvate is not as available. In other words BCAAs are able to be broken down into important substrates for cellular energy production, which aids in overall higher energy levels.
MCT's
Medium Chain Triglycerides are some what of a staple of the ketogenic diet. The structure that allows MCT's to be metabolized quickly, provides pathways for ketone production even in unadapted individuals. The uses of MCTs can range from a daily ketone boost to aiding in the elimination of the tough to deal with side effects of keto adaptation. Tryglycerides in general are made up of a glycerol bound to three fatty acids, and are ingested, stored and more commonly referred to as fats. The differentiating factor between long chain and medium chain triglycerides are the length of the fatty acids that make up their structure. These shorter, medium chain fatty acids, are metabolized in the liver so readily that they are pushed to the front of the line even before simple carbohydrates, resulting in ketone production even when carbs and glucose are present. This is the mechanism that helps decrease the lack of energy and brain fog during the short keto adaptation phase. The MCT's promote ketone production before nutritional ketosis has been reached, making up for the deficit in energy due to the considerable reduction in available energy from carbohydrates when switching to a ketogenic diet. The fact that these MCTs are broken down even before carbohydrates makes them a promising supplement even for a diet regimen including carbs, as a way to reap the benefits of the small increase in ketone production without achieving nutritional ketosis.
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In recent years the popularity of intermittent fasting for fat loss has led people to push the limits to longer term, extended fasts. This raises concerns about maintaining muscle mass, we all know that dietary protein is important to build muscle, but what about maintaining it? Over a 1 day or 2 day fast, what will happen to your muscles which were so painstaking to build.
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First let’s be clear, all weight loss diets can be boiled down to one simple concept. You are reducing your calorie intake, thereby eating less calories than you burn, this forces your body to tap into fat to make up the difference. Converting this fat into energy reduces your fat mass while making up the additional energy you need.
In order to evaluate fasting as a way to lose fat for people interested in still preserving muscle, we need something to compare it against.
Since the goal here is fat loss with a consideration for maintaining muscle, it only makes sense to compare fasting against another similarly effective method of weight loss…
A typical cutting diet; which has participants eating less calories than they consume daily , meaning they schedule their macros so their deficit shows up at the end of each day.
The story of growth hormone release starts with the interactions of two other hormones. This is detailed in a fantastic study from 1992 published in the journal of clinical endocrinology and metabolism.
The first of these hormones is responsible for triggering the release of growth hormone, and is aptly named growth hormone releasing hormone.
the other is called Somatostatin or also sometimes called growth hormone-inhibiting hormone
Throughout the day and night, there are periodic releases of GHRH which should trigger the pituitary gland to release little blips of Growth Hormone. However sometimes this doesn’t work, while sometimes a secretion of GHRH triggers a burst of GH release, if GHIH is being secreted at the same time it cancels out the effects of the GHRH and GH isn’t released.
The result is small blips of growth hormone being released throughout the day into the bloodstream. What makes it even more difficult to study is is once released, growth hormone doesn’t stick around very long, the half life is quite short, in this study the average half life of GH in the blood was just 18 minutes.
During fasting mean levels of GH in the blood increased by 3 fold.
After a closer look they found the pituitary gland had kicked into overdrive, not only did the number of blips of GH release double, the average size of each blip increased as well.
as far as why it’s happening, science isn’t entirely sure, but the mechanism is hypothesized to be a result of an increase in that growth hormone release stimulating hormone, and a simultaneous decrease in the Somostatin which suppresses release as we talked about.
As far as benefits go,
It actually turns out, evidence for growth hormone itself impacting muscle growth and maintenance is mixed. The 1988 study I referenced suggested that GH may indirectly protect muscles by helping the body mobilize fat for fuel, and also support the liver in generating small amounts of necessary glucose.
While some studies have found GH increased muscle protein synthesis, others found no real effect on it…
So what is happening?
Well remember how I mentioned that GH doesn’t stick around very long once it enters the bloodstream, one reason for this is because when it reaches the liver it is transformed into ANOTHER hormone, known as IGF-1.
Unlike Growth Hormone, IGF-1 has a robust backing of scientific evidence supporting its important role in building and maintain muscle, to the point where injectable IGF-1 is a controlled substance under anti doping laws.
There are several well studied pathways which allow for muscle growth and maintenance, IGF-1 is deeply rooted in them.
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In a previous video, we discussed 5 easy tips to lose 20 pounds. Today, we’re diving into tips that can specifically address belly fat (or weight gain around the belly) and how to lose belly fat.
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https://www.bencoomber.com – Mark Coles of M10 Fitness is back on the show, this time we delve into how Mark sets up a diet for fat loss, what the key variables are, how to tackle your calories and macronutrients, the key components for building muscle, how to set up a diet for building muscle, what supplements to take, how to train in the gym, whats better frequency of training of volume of training and his experience learning from people like Milos Sarcev. Knowledge packed show.
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Are you looking for a delicious and convenient way to incorporate keto-friendly snacks into your diet? Keto gummies are a popular option for those following a ketogenic lifestyle. These convenient and tasty treats are a great way to satisfy your sweet tooth while staying on track with your low-carb diet. In this comprehensive guide, we will explore the most effective keto gummies on the market, providing you with reviews and recommendations to help you make an informed decision.
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Keto gummies are a convenient and delicious way to enjoy a sweet treat while following a ketogenic diet. These gummies are typically low in carbohydrates and sugar, making them a great option for those looking to maintain ketosis. Additionally, many keto gummies are infused with beneficial ingredients such as collagen, MCT oil, and electrolytes, providing added health benefits beyond just a tasty snack.
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One of the main benefits of keto gummies is their portability. These snacks are easy to pack and take on the go, making them a convenient option for busy individuals or those looking for a quick and easy snack. Additionally, keto gummies are a great way to satisfy your sweet cravings without derailing your diet, making them a popular choice for those following a low-carb lifestyle.
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When shopping for keto gummies, there are a few key factors to consider to ensure you are choosing the best option for your dietary needs. First, it is important to look for gummies that are low in carbohydrates and sugar, as these are the main culprits that can kick you out of ketosis. Additionally, you may want to consider gummies that are infused with beneficial ingredients such as collagen or MCT oil for added health benefits.
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1. Perfect Keto Gummies: Perfect Keto offers a variety of keto-friendly products, including their delicious low-carb gummies. These gummies are made with high-quality ingredients and are free from artificial sweeteners and flavors, making them a great option for those looking for a clean and healthy snack.
2. SmartSweets Gummy Bears: SmartSweets offers a range of low-sugar gummy bears that are perfect for those following a ketogenic diet. These gummies are sweetened with natural ingredients and are free from sugar alcohols, making them a popular choice for those looking for a guilt-free treat.
3. ChocZero Keto Bark: While not technically gummies, ChocZero offers a delicious line of keto-friendly chocolate bark that is perfect for satisfying your sweet cravings. These bark pieces are low in carbohydrates and sugar and come in a variety of flavors to suit your taste preferences.
FAQs
1. What are keto gummies?
Keto gummies are low-carb, sugar-free snacks that are a popular option for those following a ketogenic diet. These gummies are typically made with ingredients like gelatin, erythritol, and natural flavors to create a delicious and satisfying treat.
2. Are keto gummies healthy?
Keto gummies can be a healthy snack option when consumed in moderation as part of a balanced diet. Look for gummies that are low in carbohydrates and sugar and free from artificial ingredients for the healthiest option.
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Burn fat efficiently with the kettlebell swing.
This dynamic exercise engages multiple muscle groups, boosts metabolism, and torches calories. Incorporate it into your routine for a full-body fat-burning workout.
